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JNCI Journal of the National Cancer Institute 2001 93(9):661; doi:10.1093/jnci/93.9.661
© 2001 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 93, No. 9, 661, May 2, 2001
© 2001 Oxford University Press


IN THIS ISSUE

Tamoxifen Beyond 5 Years

The National Surgical Adjuvant Breast and Bowel Project B-14 trial, a large, randomized, placebo-controlled trial of women with estrogen receptor-positive, lymph node-negative breast cancer, demonstrated that 5 years of tamoxifen treatment improves disease-free survival and overall survival. In this issue of the Journal, Fisher et al. (p. 684) present new results from the trial, based on 7 years of follow-up after the initial 5-year treatment period, that address whether tamoxifen treatment for more than 5 years provides additional benefit. The authors found that women who did not continue tamoxifen treatment beyond 5 years had a slight advantage in . . . [Full Text of this Article]

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